Testicular Gene Expression in Cryptorchid Boys at Risk of Azoospermia
نویسندگان
چکیده
منابع مشابه
Testicular gene expression in cryptorchid boys at risk of azoospermia.
Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased gonadotropin and testosterone secretion stimulate transformation of gonocytes into Ad spermatogo...
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Chobot (Poland); G Joner (Norway); D Michalkova (Slovakia); C Patterson (Northern Ireland); P Pozzilli (Italy, Lazio); AG Schranz (Malta); P Smail (Scotland); M Songini (Italy, Sardinia); B Urbonaite (Lithuania); E Wadsworth (British Paediatric Survey, UK). Funding: The European diabetes (EURODIAB) research network is supported by the European Commission medical research programme (contracts BM...
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background: deletions of the daz (deleted in azoospermia) genes within the human y chromosome's azfc region are the most common cause of spermatogenesis failure. these deletions are usually assessed by analyses of genomic dna extracted from peripheral leukocytes. daz genes are expressed in male germ cells. in this prospective study, we investigated daz expression and deletion in 102 consecutiv...
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Background: Male infertility is a common problem and needs a minimally invasive method to arrive at the appropriate diagnosis. Alternative to open testicular biopsy the fine needle aspiration cytology of the testis is being increasingly used as a minimally invasive method of evaluating testicular function. Aim of the study: To assess the diagnostic accuracy of fine needle aspiration cytology in...
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Background: Androgens are critical steroid hormones in progression of spermatogenesis process and determine the male phenotype that their actions are mediated by the androgen receptor (AR), a member of the nuclear receptor superfamily. In the Androgen receptor, transactivation domain encoded by exon 1, DNA binding domain encoded by exons 2 and 3, hinge region encoded by part of exon 4, and C-te...
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ژورنال
عنوان ژورنال: Sexual Development
سال: 2011
ISSN: 1661-5425,1661-5433
DOI: 10.1159/000323955